Phytochemical Investigation of Antimicrobial Activity Leaves Extract of Kigelia africana

Rehab Mobark, Osman Mohammed and Khidir Tajelseir Othman Mustafa

Abstract: The leaves of Kigelia africana. The family of Bignoniaceae and commonly called the ohm shutter as important source for treatment in complementary medicine. The Sudanese varieties are one of the best in the market, which prompted investigation of leaves extracts. The 96% ethanolic extract exhibited significant antimicrobial activity and highlighted the biological monitoring of activity in order to isolate the active metabolites from the chloroform extract of the leaves. The presence of sterols and triterpenes, carotenoids, coumarins, alkaloids, saponins, tannins, flavonoid and carbohydrates was confirmed by phytochemical screening of the diethyl ether, methanolic and aqueous extracts. The leaves extract was monitored by analytical and preparative TLC. From the above mention extract we prepare cream and ointment as antibacterial and antifungal dosage forms.

Keywords: phytochemical screening, extract, Kigelia africana leaves, antimicrobial activity, Minerals content.

Pages: 44 – 50 | Full PDF Paper